Research links acute malnutrition to gut microbes

WASHINGTON: A dearth of calories may not be the only reason some children face acute malnutrition, according to a new study out this week that says the microbes living in our guts may also be to blame.

Within hunger-stricken communities, not all children fare the same. Some develop acute malnutrition, while others, even their brothers and sisters, may stay healthy.

And some children respond well to treatment -- generally a peanut-based nutrient-rich supplement -- while for others, the benefits cease when the treatment does.

To figure out why this happens, researchers studied more than 300 sets of twins in Malawi, where malnutrition is a common childhood ailment, during their first three years of life.

Among half the twin pairs, one or both twins became malnourished over the course of the study.

Even among identical twins, there were cases where one twin -- but not the other -- developed a form of malnutrition called kwashiorkor, associated with swollen bellies, liver damage, skin ulcerations and loss of appetite, in addition to wasting.

That ruled out human genetics as a factor in the disorder, since identical twins share identical genomes.

But the researchers found something else at play: the microbes in the gut that extract nutrients and calories from the diet synthesise vitamins and nutrients and help shape the immune system.

When any of the twins became malnourished, both received treatment to limit food sharing.

In the healthy twin, the gut microbes thrived with the extra food and continued to mature after the treatment ended. But in the severely malnourished twin, the gut microbes stalled out or even regressed by four weeks after the treatment ended.

The findings were further bolstered when the researchers implanted into mice the gut microbes of the healthy and malnourished twins.

Both groups of mice were fed the same diet -- one similar to the nutrient-deficient diet common in Malawi -- but the ones who were transplanted with the malnourished children's microbes dropped weight, while the others did not.

"The gut microbes of malnourished children and malnourished mice do not appear to mature along a normal, healthy trajectory," said senior author Jeffrey Gordon of Washington University's Centre for Genome Sciences and Systems Biology.

"Our results suggest we need to devise new strategies to repair gut microbial communities so these children can experience healthy growth and reach their full potential."

Gordon said the new findings could be a crucial step towards finding better treatment for severely malnourished children.

"It may be that earlier or longer treatment with existing or next-generation therapeutic foods will enhance our ability to repair or prevent the problems associated with malnutrition," he said.

"We are also exploring whether it is possible to supplement the therapeutic food with beneficial gut bacteria from healthy children, as a treatment to repair the gut microbiome," he added.

"We hope that these studies will provide a new way of understanding how the gut microbiome and food interact to affect the health and recovery of malnourished children."

Their study is to be published Thursday in the US journal "Science".

According to UNICEF, a person dies of starvation every 3.6 seconds, and most of the deaths are among children under five.

"Some 300 million children go to bed hungry every day. Of these only eight percent are victims of famine or other emergency situations. More than 90 per cent are suffering long-term malnourishment and micronutrient deficiency," the UN agency says on its website.

-AFP/fl

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iPhone users pay highest phone bills

iPhone users pay higher phone bills than other smartphone consumers.

(Credit:
CBS Interactive)

Rumors of a cheaper iPhone on the horizon may come as welcome news for fans of the device -- especially because iPhone users reportedly pay the highest monthly phone bills, no matter the carrier, according to AllThingsD.

Android, Windows, and BlackBerry users spend less per month to use their smartphones, according to data by Consumer Intelligence Research Partners that was acquired by AllThingsD. It seems that the higher costs come from carriers charging more for iPhone data plans and additional wireless fees.

"We think it has to do with their data plans and carriers, rather than their usage habits," CIRP co-founder Michael Levin told AllThingsD. "They are all on expensive data plans, unlike Android users, some of which are on prepaid or unsubsidized plans with regional carriers."

The data collected is from October to December 2012 and shows that 59 percent of the iPhone users surveyed spent more than $100 per month on their plan with 10 percent of those users spending $200 or more. Only 6 percent spent $50 or less. Conversely, 13 percent of Android users spent $50 or less and 53 percent spent more than $100. Both Windows and BlackBerry users spent even less overall.

Although the monthly cost difference between the four types of devices is slight, the highest costs are still skewed toward iPhone users. This may be because iPhones are more expensive devices and carriers have to shoulder that burden.

"Given the subsidies on iPhones, the carriers are working hard to make their money back during the course of the contract," CIRP's Josh Levitz told AllThingsD. "With the exception of perhaps the hottest Android phones, we think the subsidies on Android phones are lower, so the carriers make more money even with slightly lower per-subscriber revenue."

If Apple does indeed release a cheaper iPhone, it'll be interesting to see if carriers will also lower monthly charges for the device.

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Obama: "No doubt" Congress will pass immigration, gun bills

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Obama: "No doubt" gun, immigration bills will pass in coming months

There's more bipartisan support in Congress for comprehensive immigration reform than gun control legislation, President Obama said tonight during an interview with Univision, but qualified that even under his proposal, illegal immigrants shouldn't be harboring expectations that they'll be granted citizenship "manana."

"Even under our proposal, this is not a situation where overnight, suddenly people all find themselves as citizens," Mr. Obama told the Spanish-language television network. "They're going to have to go to the back of the line. We're going to have to clear out the existing line, backlogs we have in terms of illegal immigrants, because they did it the right way. We shouldn't punish them for breaking the law.

"...What we don't want to do is to create some vague prospect in the future that somehow comprehensive immigration reform that includes a pathway to citizenship will happen manana," he continued, chuckling softly at the somewhat awkward injection of the Spanish word for "tomorrow." "But we have to put that in place at the outset, and make sure people are clear that this pathway is real and not just a fantasy for the future."

Asked whether he was in a standoff with Sen. Marco Rubio, R-Fla., the son of Cuban immigrants who has said he will not support a bill that does not put border control ahead of a path to citizenship, Mr. Obama said no, but pointed out that the number of people crossing the border illegally has dropped "about 80 percent since 2000."

On Tuesday, the president delivered a speech in Las Vegas outlining his immigration plan and applauding a bipartisan group of eight senators that has offered up proposals as well. In an interview today with another Spanish language network, Telemundo, he specified that he's hoping immigration reform that includes a pathway to citizenship can be passed in the next six months, but "certainly this year."

Meanwhile, despite facing more resistance from the right on tightening gun laws, he said he has "no doubt" that Congress will be able to put through legislation on gun control, as well as immigration.

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Obama: Legalization for illegal immigrants won't happen "ma?ana"

"On the gun issue, you're starting to see gun owners, people who traditionally have opposed gun control, saying, 'You know what, when 20 of our children are shot by somebody who is disturbed, and when it is that easy to get these high-clip magazines that can fire off hundreds of shots in a few minutes, then it's time for us to do better job on background checks, to get control of these magazine clips, to really crack down on gun trafficking," Mr. Obama said in the Univision interview.

The Senate Judiciary Committee today held the first congressional hearing on gun violence since last month's massacre at a Newtown, Conn., elementary school, that left 20 children and six adults dead. Star witnesses included former Rep. Gabrielle Giffords, D-Ariz., who survived a shot to the head two years ago during an assassination attempt that left six people dead, and her husband on one side, and NRA CEO Wayne LaPierre on the other.

Both gun control and immigration "will end up generating some opposition," the president said. "There will be passions on both sides. But I'm generally encouraged that the Senate seems to be having a serious conversation about these issues."

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Obama Confident Immigration Reform Will Pass

President Barack Obama expressed confidence on Wednesday that he would sign comprehensive immigration reform into law by the end of this year.

In an interview with Univision's Maria Elena Salinas, Obama explained that significant details of a bill still must be worked out by lawmakers, including the structure of a pathway to citizenship for many of the 11 million undocumented immigrants. But Obama said that the progress made by a bipartisan group of lawmakers in the Senate has given him hope that a deal can get done.

See Also: What Will Be Obama's Immigration Legacy?

When asked by Salinas if we will have immigration reform by the end of the year, Obama said, "I believe so."

"You can tell our audience, 'Sí, se puede?'" Salinas asked.

"Sí, se puede," Obama responded.

Later in the interview, Obama said that he hopes a bill could be passed as early as this summer.

But cognizant of deep divisions a topic like immigration has sewn in the past, Obama said that's contingent on bipartisan negotiations continuing to proceed well.

"The only way this is going to get done is if the Republicans continue to work with Democrats in Congress, in both chambers, to get a bill to my desk," he said. "And I'm going to keep on pushing as hard as I can. I believe that the mood is right."

Although the president threatened to introduce his own bill if negotiations in Congress stall during his speech in Las Vegas, Nevada, on Tuesday, he said he is content to let lawmakers hash out the details among themselves for the time being.

"If they are on a path as they have already said, where they want to get a bill done by March, then I think that's a reasonable timeline and I think we can get that done. I'm not going to lay down a particular date because I want to give them a little room to debate," he said. "If it slips a week, that's one thing. If it starts slipping three months, that's a problem."

The president's principles and the Senate's principles on immigration broadly align with one another, but there are still thorny issues that could spark a division between Obama and Republicans, such as the pathway to citizenship.

The Senate's path to citizenship would allow many undocumented immigrants to obtain legal status immediately upon passage of the law. But their ability to then seek legal permanent residency would be contingent upon the U.S.-Mexico border being deemed secure. Sen. Marco Rubio (R-Fla.), a member of the bipartisan "Gang of Eight" on immigration, has been particularly vocal in stating that border security is a precondition for gaining legal permanent residence, and then citizenship.

While the White House has said that it is withholding judgment on that plan until actual legislative language is drafted, Obama said that he wants a bill that makes it clear from the outset that undocumented immigrants eligible to earn their way to citizenship can eventually obtain it.

"What we don't want to do is create some kind of vague prospect in the future that somehow comprehensive immigration reform that includes a pathway to citizenship will happen, you know, mañana," Obama said. "We want to make sure we are very clear this legislation provides a real pathway."

The president said that enhancing border security measures and workplace enforcement provisions are a part of his plan, as well as the Senate's, and cited his administration's efforts to bulk up border security during the past four years, saying that illegal crossings have dropped 80 percent since 2000.

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Sixty-five people executed in Syria's Aleppo: activists

BEIRUT (Reuters) - At least 65 people were found shot dead with their hands bound in the northern Syrian city of Aleppo on Tuesday in a "new massacre" in the near two-year revolt against President Bashar al-Assad, activists said.

Opposition campaigners blamed the government but it was impossible to confirm who was responsible. Assad's forces and rebels have been battling in Syria's commercial hub since July and both have been accused of carrying out summary executions.

U.N.-Arab League mediator Lakhdar Brahimi told the U.N. Security Council "unprecedented levels of horror" had been reached in Syria, and that both the government and rebels had committed atrocious crimes, diplomats said.

He appealed to the 15-nation council to overcome its deadlock and take action to help end the civil war in which Syria is "breaking up before everyone's eyes".

More than 60,000 people are estimated to have been killed in the war, the longest and deadliest of the revolts that began throughout the Arab world two years ago.

The U.N. refugee agency said the fighting had forced more than 700,000 people to flee. World powers fear the conflict could envelop Syria's neighbors including Lebanon, Jordan and Turkey, further destabilizing an already explosive region.

Opposition activists posted a video of at least 51 muddied male bodies alongside what they said was the Queiq River in Aleppo's rebel-held Bustan al-Qasr neighborhood.

The bodies had what looked like bullet wounds in their heads and some of the victims appeared to be young, possibly teenagers, dressed in jeans, shirts and trainers.

Aleppo-based opposition activists who asked not to be named for security reasons blamed pro-Assad militia fighters.

They said the men had been executed and dumped in the river before floating downstream into the rebel area. State media did not mention the incident.

The British-based Syrian Observatory for Human Rights, which says it provides objective information about casualties on both sides of Syria's war from a network of monitors, said the footage was evidence of a new massacre and the death toll could rise as high as 80.

"They were killed only because they are Muslims," said a bearded man in another video said to have been filmed in central Bustan al-Qasr after the bodies were removed from the river. A pickup truck with a pile of corpses was parked behind him.

STALEMATE

It is hard for Reuters to verify such reports from inside Syria because of restrictions on independent media.

Rebels are stuck in a stalemate with government forces in Aleppo - Syria's most populous city which is divided roughly in half between the two sides.

The revolt started as a peaceful protest movement against more than four decades of rule by Assad and his family, but turned into an armed rebellion after a government crackdown.

About 712,000 Syrian refugees have registered in other countries in the region or are awaiting processing as of Tuesday, the U.N. refugee agency said.

"We have seen an unrelenting flow of refugees across all borders. We are running double shifts to register people," Sybella Wilkes, spokeswoman for the U.N. High Commissioner for Refugees (UNHCR), told Reuters in Geneva.

The United Nations said it had received aid promises ahead of a donor conference in Kuwait on Wednesday where it is seeking $1.5 billion for refugees and people inside Syria. Washington announced an additional $155 million that its said brought the total U.S. humanitarian aid to the crisis to some $365 million.

Aid group Médecins Sans Frontières said the bulk of the current aid was going to government-controlled areas in Syria and called on donors to make sure they were even-handed.

MISSILES

In the eastern city of Deir al-Zor, insurgents including al Qaeda-linked Islamists captured a security agency after days of heavy fighting, according to an activist.

Some of the fighters were shown carrying a black flag with the Islamic declaration of faith and the name of the al-Nusra Front, which has ties to al Qaeda in neighboring Iraq.

The war has become heavily sectarian, with rebels who mostly come from the Sunni Muslim majority fighting an army whose top generals are mostly from Assad's Alawite sect, an offshoot of Shi'ite Islam. Assad has framed the revolt as a foreign-backed conspiracy and blames the West and Sunni Gulf states.

Fighting also took place in the northern town of Ras al-Ain, on the border with Turkey, between rebels and Kurdish militants, the Observatory said.

In Turkey, a second pair of Patriot missile batteries being sent by NATO countries are now operational, a German security official said.

The United States, Germany and the Netherlands each committed to sending two batteries and up to 400 soldiers to operate them after Ankara asked for help to bolster its air defenses against possible missile attack from Syria.

(Additional reporting by Sylvia Westall in Kuwait, Sabine Siebold in Berlin and Stephanie Nebehay in Geneva; Editing by Andrew Heavens and Robin Pomeroy)

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Tibetans in India launch drive against China

NEW DELHI: The Tibetan government-in-exile in India on Tuesday announced plans for a four-day campaign to bring global pressure on China in a bid to end a string of self-immolations in their Himalayan homeland.

Penpa Tsering, speaker of the exiled Tibetan parliament based in the northern Indian town of Dharamshala, said the drive would include rallies and meetings and begin in New Delhi on Wednesday.

"The situation is getting more and more grim," Tsering said at a joint news conference with Lobsang Sangay, who in 2011 took over political duties from revered Buddhist spiritual leader, the Dalai Lama, and was named prime minister.

The two leaders said 99 Tibetans had set themselves on fire between 2009 and January 22 this year in protest against Chinese rule in Tibet. Of that number, the government-in-exile says 83 have died.

"Instead of trying to address the main causes as to why self-immolations are taking place, as to why Tibetans are protesting in various other forms, the Chinese government has resorted to a blame game," Sangay said.

The Havard-educated scholar said India, home to tens of thousands of Tibetan exiles, "ought to speak out forcefully on Tibet".

The four-day campaign will call for visits to Tibet by UN fact-finding teams and the publication of details of human rights discussions between Beijing and foreign powers, Sangay said.

He said the Tibetan government as well as the parliament, which has been based in Dharamshala since the Dalai Lama fled after a failed uprising against China in 1959, were determined to highlight "repression of Tibetans in Tibet".

Both the Dalai Lama and the prime minister have appealed to Tibetans not to resort to self-immolation.

"We are against drastic action but we must highlight it (the situation in Tibet) to the international community," Sangay said.

Many Tibetans in China accuse the government of religious repression and eroding their culture, as the country's majority Han ethnic group increasingly moves into historically Tibetan areas.

China rejects that, saying Tibetans enjoy religious freedom. Beijing also points to the huge ongoing investment that it says has brought modernisation and a better standard of living to Tibet.

-AFP/fl

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Uber car service battles to stay in Colorado

Uber is headed toward another obstacle from city officials, and this time it's in Denver, Colo.

The state's Public Utilities Commission is proposing changes to the rules that regulate motor vehicle transportation, which could essentially shut UberDenver down.

The transportation startup announced today that it's going to fight to keep its service in the state. Uber has created a petition for Colorado residents to sign in support of Uber. The company is also urging locals to e-mail the state's governor, John Hickenlooper, and the chairman and director of the Public Utilities Commission.

"Since our launch five months ago, Uber has made great strides in creating a convenient, efficient, and classy transportation alternative in Denver," UberDenver's general manager, Will McCollum, said in a blog post. "Uber's technology platform has improved transportation options for thousands of Denverites, and has helped grow the small businesses of hundreds of our driver partners."

The proposed changes to the motor vehicle transportation rules include bans on sedan companies charging by distance, getting within 200 feet of a restaurant, bar, or hotel, and partnering with local sedan companies.

Since Uber's business model is based on providing private transportation to customers via smartphone apps, any of these potential rule revisions could end the company's Colorado service.

"These rules are not designed to promote safety, nor improve quality of service," McCollum wrote. "They are intended to stop innovation, protect incumbents, hurt independent drivers, and shut down Uber in Denver."

However, Denver isn't the only city that's had issues with the transportation service. Uber has also faced regulatory challenges from Chicago, Washington D.C., New York, and San Francisco. In November, a class-action suit was filed against Uber in San Francisco Superior Court claiming unfair business practices. The suit claims Uber has ducked all regulations that normally govern taxicab companies.

Some of these cities have ultimately decided, however, to allow Uber to continue running its service. The company scored a victory last month when Washington D.C.'s city council unanimously approved a legislative framework for "digital dispatch" transportation services. And regulators in New York City recently approved a one-year pilot program that allows New Yorkers to hail nearby street cabs using apps like Uber.

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Grandson of oil tycoon T. Boone Pickens dies in Texas

Updated 8:35 PM ET

FORT WORTH, Texas A 21-year-old grandson of Texas oil tycoon T. Boone Pickens died Tuesday after being rushed to a hospital in Fort Worth, according to police and a family spokesman.

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Thomas Boone Pickens IV, who went by Ty, was a junior at Texas Christian University. Pickens' spokesman, Jay Rosser, called the death an "unspeakable family tragedy" and asked that the family be allowed to grieve in private.

Neither Rosser nor Fort Worth police have said what may have caused the death.

Officers were dispatched after getting a report of a dead person at an off-campus location around 9:30 a.m. Tuesday, police spokeswoman Cpl. Tracey Knight said. Police said Ty Pickens was transported to a hospital, where he was pronounced dead.

Knight said the Tarrant County medical examiner would determine the cause of death. She declined further comment.

T. Boone Pickens appears on "CBS This Morning," Aug. 23, 2012.

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CBS News

The elder Pickens made much of his fortune in oil drilling but has since become an advocate for alternative energy. The 84-year-old also is active in politics and has donated millions of dollars to his alma mater, Oklahoma State University, and various other causes.

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Jodi Arias Borrowed Gas Cans Before Killing Ex

Accused murderer Jodi Arias borrowed two five-gallon gas cans from a former boyfriend the day before she drove to Arizona to kill another ex, Travis Alexander, according to testimony in Arias' murder trial today.

In cross examination, prosecutors also forced Arias' former live-in boyfriend Darryl Brewer to describe his sex life with Arias as "pretty aggressive."

Brewer, 52, dated Arias for four years and shared a home with her in California for two years. He told the court today that Arias called him in May 2008, asking to borrow gas cans, but would not explain why. She called him again at least two more times, and arrived at his house on June 2008, to borrow the cans.

On the day she picked up the gas cans she told Brewer that she was going to visit friends in California and Arizona.

Prosecutors argue that Arias then drove to Mesa, Ariz., where she allegedly had sex with Alexander, took nude photos of him, and then stabbed him 27 times, slashed his throat, and shot him twice in the head. She is charged with murder and could face the death penalty if convicted.

Arias, who claims she killed Alexander in self defense, had approached prosecutors two years ago offering to plea to a second degree murder charge, which could carry a 25 year term, but the state rejected the offer, Nancy Grace reported on Good Morning America today.

Brewer said that Arias never returned the gas cans. The pair had been broken up two years earlier and they had only spoken "sporadically," he said.

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Prosecutors also showed receipts from Arias' trip from her California home to Alexander's home in Mesa, showing that she purchased a 10 gallons of gas at one gas station the night before she drove to Arizona, and then another 10 gallons from a different gas station 10 minutes later. Prosecutors are expected to argue she brought the gas with her to fill up her car secretly on the way to Alexander's home, showing premeditation for the murder.

Arias' attorneys called Brewer as one of their first witnesses as they began mounting their case that Arias killed Alexander in self defense, arguing that Alexander was controlling and abusive toward Arias.

They asked Brewer to explain how he and Arias had been in a stable relationship for four years, from 2002 to 2006, and had bought a home together before Arias met Alexander at a business conference and began to change.

"I saw a lot of changes in Jodi. She became a different person than I had known previously," Brewer said, describing how Arias' behavior changed in May 2006 when she joined a company called Pre-Paid Legal. There, she met Alexander and began seeing him. She continued to live with Brewer.

"She had continued to pay the mortgage, but she was not paying other household bills, she began getting into debt or financial trouble," Brewer said. "For me it seemed she was not as rational or logical."

Arias also converted to Mormonism while living with Brewer, telling him that he could no longer curse and she would no longer have sex with him because she was saving herself for marriage.

The pair had previously had an "enthusiastic" and "aggressive" sex life, Brewer admitted to prosecutors. They had engaged in anal sex, Arias had taken nude photos of Brewer, and Arias had purchased breast implants in 2006, he testified.

Brewer said that after Arias began to change, he made arrangements to move closer to his son from his first marriage, and he and Arias broke up.

They kept in touch with occasional phone calls until Arias asked to borrow the gas cans in June 2008, and then called him a week after borrowing the cans to say that her friend had been killed.

Martinez, reading notes from an interview Brewer gave to authorities during the investigation into Alexander's death, asked if Arias had ever mentioned needing an "alibi." Brewer said he did not recall any conversation about alibis.

"After this date of June 4, 2008," Martinez asked, "you received a call from Jodi Arias, and she was very agitated?"

"She was sad," Brewer said.

"Did she tell you that her friend had been killed and she did not have an alibi?"

"I don't remember that," Brewer said.

Arias was arrested a month after Alexander was found dead, in July 2008.

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French seal off Mali's Timbuktu, rebels torch library

GAO, Mali (Reuters) - French and Malian troops retook control of Timbuktu, a UNESCO World Heritage site, on Monday after Islamist rebel occupiers fled the ancient Sahara trading town and torched several buildings, including a library holding priceless manuscripts.

The United States and the European Union are backing a French-led intervention in Mali against al Qaeda-allied militants they fear could use the West African state's desert north as a springboard for international attacks.

The recovery of Timbuktu followed the swift capture by French and Malian forces at the weekend of Gao, another major town in Mali's north that had been occupied by the alliance of jihadist groups since last year.

The two-week-old mission by France in its former Sahel colony, at the request of Mali's government, has driven the Islamist rebels northwards out of towns into the desert and mountains.

Without a shot being fired, 1,000 French soldiers and paratroopers and 200 Malian troops seized Timbuktu airport and surrounded the town on the banks of the Niger River, looking to block the escape of insurgents.

In both Timbuktu and Gao, cheering crowds turned out to welcome the French and Malian troops.

A third town in Mali's vast desert north, Kidal, had remained in Islamist militant hands. But Malian Tuareg MNLA rebels, who are seeking autonomy for their northern region, said on Monday they had taken charge in Kidal after Islamist fighters abandoned it.

A diplomat in Bamako confirmed the MNLA takeover of Kidal.

A French military spokesman said the assault forces at Timbuktu were avoiding any fighting inside the city to protect the cultural treasures, mosques and religious shrines in what is considered a seat of Islamic learning.

But Timbuktu Mayor Ousmane Halle told Reuters departing Islamist gunmen had four days earlier set fire to the town's new Ahmed Baba Institute, which contained thousands of manuscripts.

UNESCO spokesman Roni Amelan said the Paris-based U.N. cultural agency was "horrified" by the news of the fire, but was awaiting a full assessment of the damage.

Ali Baba, a worker at the Ahmed Baba Institute, told Sky News in Timbuktu more than 3,000 manuscripts had been destroyed. "They are bandits. They have burned some manuscripts and also stole a lot of manuscripts which they took with them," he said.

Marie Rodet, an African history lecturer at Britain's School of Oriental and African Studies, said Timbuktu held one of the greatest libraries of Islamic manuscripts in the world.

"It's pure retaliation. They (the Islamist militant rebels) knew they were losing the battle and they hit where it really hurts," Rodet told Reuters. "These people are not interested in any intellectual debate. They are anti-intellectual."

ISLAMISTS "ALL FLED"

The Ahmed Baba Institute, one of several libraries and collections in Timbuktu containing fragile documents dating back to the 13th century, is named after a Timbuktu-born contemporary of William Shakespeare and houses more than 20,000 scholarly manuscripts. Some were stored in underground vaults.

The French and Malians have encountered no resistance so far in Timbuktu. But they will now have to comb through a labyrinth of ancient mosques, monuments, mud-brick homes and narrow alleyways to flush out any hiding fighters.

The Islamist forces comprise a loose alliance that groups Al Qaeda in the Islamic Maghreb (AQIM) with Malian Islamist group Ansar Dine and AQIM splinter MUJWA.

They have retreated in the face of relentless French air strikes and superior firepower and are believed to be sheltering in the rugged Adrar des Ifoghas mountain range, north of Kidal.

The MNLA Tuareg rebels who say they now hold Kidal have offered to help the French-led offensive against the al Qaeda-affiliated Islamists. It was not clear, however, whether the French and Malians would steer their offensive further towards Kidal, or hold negotiations with the MNLA.

FRANCE: MALI "BEING LIBERATED"

The world was shocked by Timbuktu's capture in April by Tuareg fighters, whose separatist rebellion was later hijacked by Islamist radicals who imposed severe sharia (Islamic law).

Provoking international outrage, the Muslim militants - who follow a more radical Salafist brand of Islam - destroyed dozens of ancient shrines in Timbuktu sacred to Sufi Muslims, condemning them as idolatrous and un-Islamic.

They also imposed a strict form of Islamic law, or sharia, authorizing the stoning of adulterers and amputations for thieves, while forcing women to go veiled.

On Sunday, many women among the thousands of Gao residents who came out to celebrate the rebels' expulsion made a point of going unveiled. Other residents smoked cigarettes and played music to flout the bans previously imposed by the rebels.

Hundreds of troops from Niger and Chad have been brought to Gao to help secure the town.

"Little by little, Mali is being liberated," French Foreign Minister Laurent Fabius told France 2 television.

Speaking at a news conference in Paris, French President Francois Hollande said French troops would take a step back once the job of retaking key towns was complete, and Malian and other African troops would take over the task of hunting the rebels.

"They are the ones who will go into the northern part, which we know is the most difficult because that's where the terrorists are hiding," Hollande said.

As the French and Malian troops thrust into northern Mali, African troops for a U.N.-backed continental intervention force for Mali, expected to number 7,700, are being flown into the country, despite severe delays and logistical problems.

Outgoing African Union Chairman President Thomas Boni Yayi of Benin scolded AU states at a weekend summit in Addis Ababa for their slow response to assist Mali while former colonial power France took the lead in the military operation.

Burkina Faso, Benin, Nigeria, Senegal, Togo, Niger and Chad are providing soldiers for the AFISMA force. Burundi and other nations have pledged to contribute.

AU Peace and Security Commissioner Ramtane Lamamra said these regional troops could play a useful "clean-up" role once the main military operations against the Islamist rebels end.

Speaking in Addis Ababa on Monday, U.N. Secretary-General Ban Ki-moon said the U.N. was "actively considering" helping the troop-contributing African countries with logistical support.

(Additional reporting by Richard Valdmanis in Sevare, Mali, Bate Felix and David Lewis in Dakar, Maria Golovina in London, Alexandria Sage, Vicky Buffery and Emmanuel Jarry in Paris, Tiemoko Diallo in Bamako, Abdoulaye Massalatchi in Niamey, Richard Lough and Aaron Masho in Addis Ababa; Writing by Pascal Fletcher; Editing by Andrew Heavens)

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